Ran DESeq2 for females only, males only, and combined not accounting for sex. Volcano plots, PCAs, and heatmaps of the top 30 most differentially expressed included for each.
Number of lncRNAs with < 0.05 p-values
- Females: 1
- Males: 5
- Combined: 2
Females - OA vs Control
No obvious clustering as a whole.
Control grouped with control and exposed grouped with exposed for the top 30.
Males - OA vs Control
Clustering of most males.
Control grouped with control and exposed grouped with exposed for the top 30.
Combined (Males and Females ignoring sex) - OA vs Control
Clustering consistent for males.
Grouping based on sex.